Zogulitsa
2,4-Diamino-6-hydroxypyrimidine 2,6-Diamino-4-Hydroxyprimidine
Synonyms:4 (1H) -Pyrimidinone,2,6-diamino- (8CI,9CI);2,4-Diamino-6-hydroxypyrimidine;2,4-Diamino-6-pyrimidinone;2,6-Diamino-3,4 -dihydropyrimidin-4-imodzi; 2,6-Diamino-4 (1H) -pyrimidinone;2,6-Diamino-4 (3H) -pyrimidinone;2,6-Diamino-4-hydroxypyrimidine;2,6-Diamino-4 -pyrimidinol;2,6-Diaminopyrimidin-4-imodzi;2,6-Diaminopyrimidine-4 (3H) -imodzi;6-Aminoisocytosine;6-Hydroxy-2,4-pyrimidinediamine;NSC 44914;NSC 680818;NSC9302;
Mankhwala Katundu wa 2,4-Diamino-6-hydroxypyrimidine
● Maonekedwe/Mtundu: zoyera zolimba
● Kupanikizika kwa Nthunzi: 0.00232mmHg pa 25°C
● Malo Osungunuka: 285-286 °C (dec.)(lit.)
● Refractive Index:1.7990 (chiwerengero)
● Malo Owira: 288.5 °C pa 760 mmHg
● PKA:10.61±0.50(Zonenedweratu)
● Malo Ong'anima:128.3 °C
● PSA: 98.05000
● Kuchulukana: 1.84 g/cm3
● LogP: 0.50900
● Kutentha Kosungirako: Kutentha pa +4°C
● Zomverera bwino.: Sizimva Kuwala
● Kusungunuka.:DMSO (Pang'ono), Methanol (Pang'ono)
Ungwiro/Ubwino
99% *zochokera kwa ogulitsa osaphika
2,4-Diamino-6-hydroxypyrimidine *deta kuchokera kwa ogulitsa reagent
Safty Information
● Zithunzi:
Xi
● Zizindikiro Zowopsa:Xi
● Mawu:36/37/38
● Malangizo a Chitetezo: 22-24/25-36-26
Mafayilo a MSDS
Zothandiza
● Kufotokozera: 2,4-Diamino-6-hydroxypyrimidine (DAHP) ndi inhibitor yosankha, yeniyeni ya GTP cyclohydrolase I, mlingo wochepetsera mlingo wa de novo pterin synthesis.M'maselo a HUVEC, IC50 yoletsa BH4 biosynthesis ndi pafupifupi 0.3 mM.DAHP itha kugwiritsidwa ntchito kuletsa kupanga NO mumitundu ingapo yama cell.
● Ntchito: 2,4-Diamino-6-hydroxypyrimidine (DAHP) ndi chosankha, choletsa choletsa cha GTP cyclohydrolase I, mlingo wochepetsera sitepe ya de novo pterin synthesis.M'maselo a HUVEC, IC50 yoletsa BH4 biosynthesis ndi pafupifupi 0.3 mM.DAHP itha kugwiritsidwa ntchito poletsa kupanga NO m'mitundu ingapo ya ma cell.[Cayman Chemical] Imayima pa chiyambi cha enzyme-catalyzed cascade yomwe imayamba ndi ma carbohydrate a carbon 7 ndipo amatha ndi onunkhira amino zidulo phenylalanine, tyrosine, ndi tryptophan. 2,4-Diamino-6-hydroxypyrimidine (cas# 56-06-4) ndi pawiri zothandiza organic synthesis.
2,4-Diamino-6-hydroxypyrimidine ndi mankhwala pawiri ndi molecular chilinganizo C4H6N4O.Amagwiritsidwa ntchito ngati gawo lapakati pakupanga zinthu zosiyanasiyana, kuphatikizapo mankhwala opangira mankhwala ndi dyes.Pawiriyi imakhala ndi mphete ya pyrimidine yomwe imakhala ndi magulu awiri a amino (NH2) ndi gulu limodzi la hydroxyl (OH) lomwe limagwirizanitsidwa ndi maatomu a carbon.Kapangidwe kameneka kamapangitsa kuti pakhale njira yomangamanga yopangira mamolekyu ovuta kwambiri.2,4-Diamino-6-hydroxypyrimidine angapezeke ndi njira zosiyanasiyana zopangira, kuphatikizapo zomwe cyanamide ndi urea.Lili ndi ntchito zingapo m'makampani opanga mankhwala, makamaka popanga mankhwala oletsa khansa ndi maantibayotiki.
