Malo
2,4-Diamina-6-hydroxyrididine; Cas No.: 56-06-4
Synonyms: 4 (1h) -yridididinone, 2,6-diaminafo- (8Ci, 9CI); 2,4-diaminaso-6-hydropyrididididine; 2,6-diaminidone; 2,6 2,6-diaminaso-4-hydroxyrididine; 2,6-diaminopyol; 6-aminopyopyol; 44914; NSC 680818; NSC9302;
Katundu wa mankhwala a 2,4-diaminaso-6-hydropysiridine
● Maonekedwe / mtundu: zoyera
● Mavuto a VAPOR: 0.00232mhg pa 25 ° C
● Malo osungunuka: 285-286 ° C (Dise.)
● Mndandanda woyipa: 1.7990 (kuyerekezera)
● Mowotcha: 288.5 ° C pa 760 mmhg
● PKA: 10.61 ± 0,50 (Enet)
● Maudzu: 128.3 ° C
● pssa: 98.05000
● Kuchulukitsa: 1.84 g / cm3
● Logp: 0.50900
● Kufatsa temp.:dekiccate pa + 4 ° C
● Womvera
● Solsubility.:dmso (pang'ono), methanol (pang'ono)
Zambiri zopanda chitetezo
● Petergogm (s):
Xi
● Ma Code Zowopsa: XI
● Nkhani: 36/37/38
● Nkhani zotetezeka: 22-24 / 25-36-26
Chofunika
● Kufotokozera: 2,4-Diamina-6-hydroxypyrididididididine (dahp) ndi osankha, osakhazikika a GTP Cyclohrolase I, sitepe yotsika mtengo ya desin ptertethes. Mu maselo a HAVEC, ic50 ya zoletsa bh4 biosyynthesis ndi pafupifupi 0,3 mm. Dahp itha kugwiritsidwa ntchito kutseka bwino popanda kupanga mitundu ingapo.
● Kugwiritsa ntchito: 2,4-diamina-6-hydroxyrindyrididididididine (dahp) ndi osankha, osakhazikika a GTP Cyclohrolase I, sitepe yotsika mtengo kwa desin ptern. Mu maselo a HAVEC, ic50 ya zoletsa bh4 biosyynthesis ndi pafupifupi 0,3 mm. Dahp itha kugwiritsidwa ntchito moyenera popanda kupanga mitundu ingapo yam'manja. zothandiza mu kapangidwe kake.
2,4-diamina-6-hydroxyrippyridididine ndi mankhwala ophatikizika ndi mawonekedwe a c4h6n4o. Nthawi zambiri imagwiritsidwa ntchito ngati gawo lapakati pa kapangidwe ka mankhwala osiyanasiyana, kuphatikizapo mankhwala osokoneza bongo komanso utoto. Kapangidwe kameneka kamapangitsa kuti ikhale yomanga nyumba yopanga ma molekyulu ovuta kwambiri.2,4-diaminaso-6-hydropyridididididididine, kuphatikizapo zomwe Cleamamide ndi Ureamide. Ili ndi ntchito zingapo m'makampani opanga mankhwala, makamaka mu kapangidwe ka mankhwala a anticancer komanso maantibaotrall, 2,4-diaminaso-6-hydropyrididididine ndi mankhwala othandiza omwe amagwiritsa ntchito mankhwala osiyanasiyana.
Mawu owonjezera
2,4-diamina-6-hydroxyrippyridididine ndi mankhwala ophatikizika ndi mawonekedwe a c4h6n4o. Ndi gawo lokhazikika la banja la pintidine. Pawiri ili ndi mtundu wa pino, magulu awiri a amino (nh2) amalumikizidwa pa 2-udindo ndi malo ogwiritsira ntchito, ndi gulu la hydroxyl. Kapangidwe ka mankhwala katha kufotokozedwa monga: ammonia | | H - C - C - n - c - Nh2 | | oh 2,4-diaminaso-6-hydroypypysipyridididididine ali ndi mapulogalamu osiyanasiyana m'makampani opanga mankhwala. Ndi gawo lofunikira mu kapangidwe ka mankhwala ambiri, kuphatikiza mankhwala osokoneza bongo komanso antitumor. Amagwiritsidwanso ntchito kutulutsa ma analogi angapo a nucleotide omwe amagwiritsidwa ntchito pofufuza mankhwala.
Kuphatikiza pa ntchito zamankhwala za m'ma 4,4-diaminaso-6-hydropypypypypypypypypypypypypypypyhypypyridididine imagwiritsidwanso ntchito ngati mankhwala ku Agrochemicals. Ndi chofunikira kwambiri pakuphatikizika kwa oyang'anira chomera ndi fungicides. Ndikofunikira kwambiri kutsatira njira yoyenera yogwiritsira ntchito 2,4-diaminaso-6-hydropypypypypyjididine. Popeza zimawerengedwa ngati mankhwala osasamalidwa, ziyenera kusamalira ndi zida zoteteza bwino ziyenera kuvala kuyang'anitsitsa mwachindunji.
Mwachidule, 2,4-diaminio-6-hydroxyrindyridididididine ndi malo opangira zojambulajambula ndi magawo a minda yamalamafoni ndi ulimi. Kapangidwe kake kamapangitsa kuti ikhale yothandiza ngati yapakatikati mu kapangidwe ka mankhwala a mankhwala ndi chomera chomera.
