Zogulitsa
2,4-Diamino-6-hydroxypyrimidine
Hydroxypyrimidine Chemical Properties
| Malo osungunuka | 285-286 °C (dec.) (kuyatsa) |
| Malo otentha | 234.22 ° C (kuyerekeza molakwika) |
| kachulukidwe | 1.3659 (kuyerekeza movutikira) |
| refractive index | 1.7990 (chiyerekezo) |
| kutentha kutentha. | Khalani pamalo amdima, M'mlengalenga, Kutentha kwachipinda |
| kusungunuka | DMSO (Pang'ono), Methanol (Pang'ono) |
| pka | 10.61±0.50 (Zonenedweratu) |
| mawonekedwe | Ufa Wabwino wa Crystalline |
| mtundu | Zoyera mpaka zonona |
| Zomverera | Kuwala Kumverera |
| Merck | 14,2981 |
| Mtengo wa BRN | 125006 |
| InChIKey | SWELIMKTDYHAOY-UHFFFAOYSA-N |
| CAS DataBase Reference | 56-06-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 4 (1H) -pyrimidinone, 2,6-diamino- (56-06-4) |
| EPA Substance Registry System | 2,6-Diamino-4(1H)-pyrimidinone (56-06-4) |
Kufotokozera Kwazinthu za Hydroxypyrimidine
2,4-Diamino-6-hydroxypyrimidine ndi mankhwala pawiri ndi molecular chilinganizo C4H6N4O.Ndi organic pawiri wa banja pyrimidine.Gululi lili ndi mawonekedwe a mphete ya pyrimidine, magulu awiri a amino (NH2) amagwirizanitsidwa pa 2-position ndi 4-position, ndipo gulu la hydroxyl (OH) limagwirizanitsidwa pa 6-position.Mapangidwe a mankhwala amatha kufotokozedwa ngati: Ammonia || |H--C--C--C--N--C--C--NH2 || oh 2,4-Diamino-6-hydroxypyrimidine ali ndi ntchito zosiyanasiyana m'makampani opanga mankhwala.Ndikofunikira pakati pa kaphatikizidwe ka mankhwala ambiri, kuphatikiza antiviral ndi antitumor mankhwala.Amagwiritsidwanso ntchito kupanga ma nucleotide analogues angapo omwe amagwiritsidwa ntchito pofufuza zamankhwala.
Kuphatikiza pa mankhwala opangira mankhwala, 2,4-diamino-6-hydroxypyrimidine amagwiritsidwanso ntchito ngati chogwiritsidwa ntchito mu agrochemicals.Ndiwofunikira kwambiri pakuphatikizika kwa zowongolera kukula kwa mbewu ndi fungicides.Ndikofunikira kwambiri kutsatira ndondomeko yoyenera yachitetezo mukamagwiritsa ntchito 2,4-diamino-6-hydroxypyrimidine.Popeza ili m’gulu la mankhwala oti irritant, iyenera kusamaliridwa mosamala ndi kuvala zida zokwanira zodzitetezera kupeŵa kukhudza mwachindunji.
Mwachidule, 2,4-diamino-6-hydroxypyrimidine ndi organic pawiri ndi ntchito m'minda mankhwala ndi ulimi.Kapangidwe kake ka mankhwala kumapangitsa kuti ikhale yothandiza ngati yapakatikati pakupanga mankhwala ndi owongolera kukula kwa mbewu.
Zambiri Zachitetezo
| Zizindikiro Zowopsa | Xi |
| Ndemanga Zowopsa | 36/37/38 |
| Ndemanga za Chitetezo | 22-24/25-36-26 |
| WGK Germany | 3 |
| Zowopsa | Zokwiyitsa |
| TSCA | Inde |
| HS kodi | 29335995 |
Kugwiritsa Ntchito Hydroxypyrimidine Ndi Kaphatikizidwe
| Kufotokozera | 2,4-Diamino-6-hydroxypyrimidine (DAHP) ndi choletsa, choletsa cha GTP cyclohydrolase I, mlingo wochepetsera sitepe ya de novo pterin synthesis.M'maselo a HUVEC, IC50kwa kuletsa kwa BH4biosynthesis ndi pafupifupi 0.3 mm.DAHP itha kugwiritsidwa ntchito kuletsa kupanga NO mumitundu ingapo yama cell. |
| Chemical Properties | Zoyera Zolimba |
| Ntchito | 2,4-Diamino-6-hydroxypyrimidine (DAHP) ndi choletsa, choletsa cha GTP cyclohydrolase I, mlingo wochepetsera sitepe ya de novo pterin synthesis.M'maselo a HUVEC, IC50 yoletsa BH4 biosynthesis ndi pafupifupi 0.3 mM.DAHP itha kugwiritsidwa ntchito kuletsa kupanga NO mumitundu ingapo yama cell.[Cayman Chemical] |
| Ntchito | Zimayima kumayambiriro kwa enzyme-catalyzed cascade yomwe imayamba ndi carbon-7 carbon carbohydrate ndipo imathera ndi amino acid onunkhira phenylalanine, tyrosine, ndi tryptophan. |
| Ntchito | 2,4-Diamino-6-hydroxypyrimidine (cas# 56-06-4) ndi pawiri zothandiza organic synthesis. |
| Njira Zoyeretsera | Imapangidwanso kuchokera ku H2O.[Beilstein 25 III/IV 3642.] |
