6-Methyluracil 2,4-Dihydroxy-6-methylpyrimidine

● Kumwetulira kwa Canonical: CC1=CC(=O)NC(=O)N1
● Ntchito: 6-Methyluracil (cas# 626-48-2) ndi mankhwala othandiza mu organic synthesis.6-Methyluracil, yomwe imatchedwanso thymine kapena 5-methyluracil, ndi organic compound ndi mankhwala a C5H6N2O2.Ndiwochokera ku pyrimidine komanso gawo la nucleic acid.Thymine, pamodzi ndi adenine, cytosine, ndi guanine, ndi imodzi mwa nucleobases inayi yomwe imapezeka mu DNA. Thymine imagwira ntchito yofunika kwambiri mu DNA pophatikizana ndi adenine kudzera mu hydrogen bonding, kupanga imodzi mwa awiriawiri apansi omwe amapanga mawonekedwe awiri a helix.Makamaka, thymine imapanga zomangira ziwiri za haidrojeni ndi adenine mu DNA.Mu RNA, uracil imalowa m'malo mwa thymine komanso imapanga awiriawiri okhala ndi adenine. Thymine ili ndi udindo wonyamula chidziwitso cha majini mkati mwa molekyulu ya DNA.Zimakhala ngati ndondomeko ya kaphatikizidwe ka mapuloteni ndipo zimagwira ntchito yofunika kwambiri pakufalitsa makhalidwe a chibadwa kuchokera ku mibadwomibadwo kupita ku wina.Kupatulapo ntchito yake mu DNA ndi RNA, thymine imagwiranso ntchito ngati cholinga chofunika kwambiri pa mankhwala osokoneza bongo.Mankhwala ena a chemotherapeutic amayang'ana ma enzyme omwe amapangira thymine, motero amalepheretsa kukula kwa maselo a khansa.Pogwira ntchito ya thymine, ndikofunika kutsatira ndondomeko zoyenera zachitetezo cha labotale, kuphatikizapo kuvala zida zoyenera zodzitetezera ndikugwira ntchito pamalo opuma mpweya wabwino.Kuonjezera apo, thymine iyenera kusungidwa pamalo owuma ndi ozizira kuti asawonongeke ndikusunga bata.