Malo
Di-Ter-Butyl Dicarbonate; Cas No.: 24424-99-5
Mawuno: Bis (TOrt-nthoxycanyl) oxide; 2) o cpd; di-tityl pycarbonate
Katundu wa mankhwala a di-tert-butyl dicarbonate
● Maonekedwe / mtundu: zoyera kuti mafuta oyera
● Mavuto a Vapor: 0.7mhmhg pa 25 ° C
● Malonjezo: 22-24 ° C
● Mndandanda woyipa: 1.4090
● Kutentha: 235.8 ° C pa 760 mmhg
● Maudzu: 103.7 ° C
● psa:61.83000
● Kuchulukitsa: 1.054 g / cm3
● Logp: 2.87320
● Malo osungirako.
● Chovuta.:Moiverre tcheru
● Madzi osungunuka.
● xlogp3: 2.7
● Mphaka Hydrogen Conser Wopereka: 0
● Ovomerezeka a Hydrogen Commet Command: 5
● Mgwirizano wozungulira: 6
● Misa yeniyeni: 218.11542367
● Atomu olemera: 15
● Zovuta: 218
Zambiri zopanda chitetezo
● Petergogm (s):
T, t +,
F, F +,
Xi
● TODI yowopsa :, t, f, xi, f +
● Nkhani: 11-16-26-36 / 37 / 38-43-10-40
● Nkhani zotetezeka: 16-26-28-36 / 37-5-7 / 9-37 / 39-24-36 / 37-33
Chofunika
Maphunziro a Mankhwala:Makalasi ena - ma etter, ena
Kumwetulira kwa Canonan:CC (c) (c) OC (= o) oc (= o) oc (c) (c) c
Gwiritsani Ntchito:Di-Ter-Butyl Dicarbonate (Boc2o) amagwiritsa ntchito kwambiri kuyambitsa magulu otetezedwa omwe amateteza matenda a Peptide. Imagwira ntchito yofunika pokonza 6-acetyl-1,2,3-tetraphroproridine poyankha ndi 2-piperonene. Imagwira ngati gulu loteteza lomwe limagwiritsidwa ntchito potengera kaphatikizidwe.
Mawu owonjezera
Di-Ter-Butyl Dicarbonatendikumagwiritsa ntchito mawonekedwe a synthec. Amadziwikanso kuti T-Boc Teyhydride kapena Boc Tendydride. Nthawi zambiri imagwiritsidwa ntchito kuteteza magulu a amine ntchito pogwiritsa ntchito mankhwala. Di-Tert-Butyl Dicarbonate amagwira ndi Amines kuti apange zotumphukira za mavatamate, ndikuteteza kwakanthawi kwa gulu la Amine. Mukafuna zomwe akufuna ali nazo kwathunthu, gulu la carbamate imatha kuchotsedwa mosavuta ndi chithandizo cha asidi, kulolera magwiridwe oyambilira a amine. Ili ndi njira yothandiza yosinthira magulu ena ogwirira ntchito m'mamolekyulu achilengedwe.
Karata yanchito
Kuphatikiza pa kuteteza magulu a amine, di-tly-butyl dicarbonate ali ndi mapulogalamu enanso mu synthesis:
Kuteteza magulu a hydroxyl:Di-Ter-butyl dicarbonate akhoza kuchitira ndi mowa kuti apange kaboni, kuteteza gulu la hydroxyl. Gulu la Carbonate limatha kuchotsedwa pogwiritsa ntchito malo oyenera, kulola kusintha kwa mitundu ina ya magwiridwe antchito.
Zochita za carbonus:Di-Ter-butyl dicarbonate imatha kugwiritsidwa ntchito ngati gwero la kaboni monoxide mu carbonulation zochita. Zimakhudzana ndi zigawo zamitundu monga Amine, mowa, ndi thiols kuti apange zinthu za carbonano.
Kukonzekera kwa acid chlorides:Kuyankha Di-Ter-Butyl Dicarbonate yokhala ndi Thonyl chloride kapena oxalyl chloride amalola zofalitsa zofananira acid. Acid chlorides ndi ma reagents osinthasintha omwe amagwiritsidwa ntchito m'malo osiyanasiyana.
Pulogalamu Yokhazikika Yokhazikika:Di-Ter-Butyl Dikirborbonate imagwiritsidwa ntchito poteteza komanso kukwapula masitepe mu kaphatikizidwe ka peptide. Amagwiritsidwa ntchito kuteteza amino acid nthawi yayitali ndikuchotsa magulu oteteza kuti apange magulu a amino kuti agwirizane pambuyo pake.
Makulidwe a Polymerizan:Di-Ter-Butyl Dicarbonate akhoza kukhala ngati wothandizirana ndi unyolo pamavuto a polymerization. Itha kuchitira ndi maunyolo akukula polymer, kuthetsa kukula kwawo kapena kupanga masamba atsopano.
Awa ndi zitsanzo zochepa chabe za ntchito zambiri za di-Tert-butyl dicarbonate mu kapangidwe kosiyidwa. Kugwiritsa ntchito mosiyanasiyana komanso kusagwiritsa ntchito kumapangitsa kuti ikhale yosangalatsa m'masinthidwe osiyanasiyana.
