Malo
Mapaipi; Cas No.: 5625-37-6
Mananoms:1,4-piperaznetienhane sulmonon acid;
1,4-piperaznienesismbonic acid;
1,4-piperazinethalfonalfonalfonalfonalfonate-n, n'-ethanesic acid);
Piperazine-n, N'-Ethanelfonic acid), mchere wa sodium; mapaipi
Mankhwala Othandizira mapaipi
● Maonekedwe / mtundu: zoyera / zoyera za crystalline ufa
● Malo osungunuka:> 300 ° C (yoyatsidwa.)
● Cholinga chosinthika: 1.6300 (kuyerekezera)
● PKA: 6.8 (pa 25 ℃)
● psa: 131.98000
● Kuchulukitsa: 1.505 g / cm3
● Logp: 0.41700
● Kufatsa temp.:
● Solsubility.:0.1 m Naoh: 0.25 g / ml, omveka, opanda utoto
● Madzi osungunuka.:Ableble m'madzi.
● xlogp3: -6.7
● Hydrogen Conser Wopereka: 2
● Undrogen Corm Command Condiraor: 8
● Mgwirizano wozungulira: 6
● Misa yeniyeni: 302.06062865
● Atomu olemera: 18
● Zovuta: 397
Kuyera / mtundu
99% * deta kuchokera kwa ogulitsa zikwangwani
1,4-piperazinebis (ethanesicacid) 99% * deta kuchokera kwa ogulitsa
Zambiri zopanda chitetezo
● Petergogm (s):
Xi
● Ma Code Zowopsa: XI
● Nkhani: 36/37/38
● Nkhani zotetezeka: 22-24 / 25-37 / 39-26
Chofunika
Maphunziro a Mankhwala:Zogwiritsa Ntchito Zina -> Zithunzi Zobisika
Kumwetulira kwa Canonan:C1CN (CCN1CCS (= O) (= o) o) o) ccs (= o) (= o) o
Gwiritsani Ntchito:Piperazine-n, n'-ethanesphonic acid) Ultra -p> 9.5%) ndi mankhwala ofunikira mankhwala a mitundu yonse ya mankhwala. 1,4-piperaznieneunesfonic acid, piperazine-n, n'-ethanelfonic njira yogwiritsira ntchito zachilengedwe kuyambira pa madigiri 20 Celsius. Wothandizila Wogulitsa ndi PKA pafupi ndi Luwialogine Ph.Pipes [Piperazine-n, N'-ethanelfonic acid)] Ndi Ethanesfonic acid Buffer yopangidwa ndi zabwino et al. Mu 1960s. Mapaipi ali ndi PKA pafupi ndi PH yomwe imapangitsa kuti ikhale yothandiza pantchito ya cell. Zalembedwa kuti muchepetse kuchepa Lipid mukamawononga histaloushyde mu hitalogy mu chomera ndi nyama.Dunt, mitundu, mapipe, sesquisodium; Mapapes dipotium mchere; Mapaipi diadium mchere; Mapaipi, mchere wa sodium. Bubsers ikhoza kukonzekera njira yothetsera maziko kuti mapaipi aulere a acipe, kapena kusakaniza njira zoyenera za monooodium, kutengera mchere wa ph. Mapaipi, amagwiritsidwa ntchito wothandizila ku Biocheminsistry. Mapaipi ali ndi PKA (6.76 pa 25 ° C zomwe zimapangitsa kuti zizigwira ntchito pafoni. Protocols zanenedwapo pa kugwiritsa ntchito mapaipi kuti alekanitse a Glymoxyted RNA ku Guels ku Agar, Kupanga Mapu a RNA, ndi ringnucase kutetezedwa. Mapaipi agwiritsidwa ntchito ngati buffer mu glutaralyerdehyde kukhazikika kwa minyewa. Mapaipi alimbikitsidwa kuti agwiritsidwe ntchito mu kafukufuku wa mu kafukufuku wa Castro of Caspases 3, 6, 7, ndi 8. Mapaipi agwiritsidwa ntchito mu chikhalidwe cha cell pazinthu monga ukadaulo wa nembanemba mapuloteni ku Estherherichia Coli.
Mawu owonjezera
Mapaipi aulere, omwe amadziwikanso kuti 1,4-piperaznieneonelyfonic acid, ndi wabwino kwambiri wokhala ndi mtengo wofanana ndi wakhungu wamba PH. Monga, mapaipi aulere nthawi zambiri amagwiritsidwa ntchito ngati buffer yofufuzira kafukufuku wazofufuza zinthu zakale. Mapaipi alibe kuthekera kopanga zitsulo zambiri ndi zitsulo zambiri ndipo amalimbikitsidwa kuti azigwiritsa ntchito ngati buffer yosagwirizanitsa yothetsera ma ions achitsulo. Mapaipi ali ndi ntchito zosiyanasiyana ndipo amagwiritsidwa ntchito kwambiri mu cell studio, mu protein crystallization, ngati buffer yothamanga mu gel ectrokhores, komanso ngati ectomlectric kuyang'ana kwambiri ndi chromatographyc. Buffer iyi imatha kupanga ma radicals ndipo motero sioyenera kusintha kwa Redox. Ndioyenera kugwiritsa ntchito mu bicinchoninic acid (BCA). Kusungunuka kwa mapaipi kumawonjezeka pomwe asidi waulere amasinthidwa kukhala mchere wa sodium.Bufels amapangidwa ndi kuwonjezera njira yothetsera ma piacos acipe ndi kulumikizidwa ku Ph
Mapaipi ndi membala wa ku Ethanesis acid plaffer, woyamba amadziwitsa ena a al. Popeza PKA yake pa 37 ° C ili pafupi ndi thupi pH, mapaipi ali ndi ntchito mu chikhalidwe cha mkhalidwe.
Mawu owonjezera
Mapaipi, omwe amadziwikanso kuti piperazine-n, n'-ethanelfonic acid), ndi buffer yomwe imagwiritsidwa ntchito pofufuza kwachilengedwe ndi kafukufuku wazomwe amagwiritsidwa ntchito pofufuza zachilengedwe komanso kafukufuku wazomwe amagwiritsidwa ntchito pofufuza zachilengedwe komanso kafukufuku wazomwe amagwiritsidwa ntchito pofufuza zachilengedwe komanso kafukufuku. Ndi zipatso za Zwitteric zomwe zimathandizira kusunga ph ph yokhazikika pamatumba am'madzi.
Chimodzi mwazinthu zoyambirira za mapaipi ali m'munda wa biology sayansi ya ma biology ndi biochemistry, komwe amagwiritsidwa ntchito ngati buffer pokonzekera ndikusungira zitsanzo za zitsanzo. Mapaipi ali ndi phindu la PKA pafupifupi 7.46, lomwe limapangitsa kuti likhale labwino kuti lisakhale ndi kutentha kwa 6.7 mpaka 7.9 pamatemberero (pafupifupi madigiri 37 Celsius).
Mapaipi amakhala othandiza kwambiri kuti asunge Ph nthawi yokhazikika ngati kuyeretsa mapuloteni, enzyme, ndi gel ectophboresis. Zimathandizira kuchepetsa zosintha za pH zomwe zitha kukhudza kapangidwe kake ndi ntchito yamapuloteni ndi ma enzyme.
Kugwiritsanso ntchito kwina kulikonse kafukufuku wa cell. Nthawi zambiri imagwiritsidwa ntchito ngati buffer yokhala ndi zikhalidwe za cell. Mapaipi amathandiza kusungabe ph pH nthawi zonse mu kukula, komwe ndikofunikira kuti kukula ndi kuthedwa kwa maselo. Imaperekanso khola kuti muphunzire njira zamagalimoto komanso zomwe zimapangitsa kuyeseza.
Mapaipi amagwiritsidwanso ntchito m'maluso osiyanasiyana owunikira, monga mankhwala amadzimadzi ndi capillary electrophoresis. Kukhazikika kwake kwa mafakita ndi ph pH kumapangitsa kuti ikhale yoyenera kugwiritsa ntchito njirazi, pomwe njira yotsimikizika yotsimikizika ndiyofunikira pazotsatira zolondola.
Kuphatikiza apo, mapaipi apeza mapulogalamu popanga mankhwala osokoneza bongo ndi mabungwe operekera. Itha kugwiritsidwa ntchito ngati buffer mu mankhwala ogulitsa mankhwala kuti athetse kusanza mankhwala osokoneza bongo ndikuwonjezera mayamwidwe osokoneza bongo.
Ponseponse, mapaipi ndi othandizira osokoneza bongo omwe ali ndi ntchito zosiyanasiyana pakufufuza kwachilengedwe komanso kafukufuku wazomwe amapezeka pafoni, njira zowunikira, ndi mapangidwe a mankhwala osokoneza bongo. Kutha kwake kukhalabe ndi pungula kumapangitsa kuti kukhala chida chamtengo wapatali m'minda yama sayansi.
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