Malo
Pididine-2,4 (1h, 3h) -dione; Cas No.: 66-22-8
Mawuno: UCHIL
Chuma cha PYYIDIINE - 2,4 (1h, 3h) -DIone
● Maonekedwe / mtundu: ufa woyera
● Mavuto a VAPOR: 2.27E-08mmhg pa 25 ° C
● Malo osungunuka:> 300 ° C (yoyatsidwa.)
● Indeys RefeortAx: 1.501
● Kutentha: 440.5 ° C pa 760 mmhg
● PKA: 9.45 (pa 25 ℃)
● Kuwala kwa Flash: 220.2OC
● psa:65.72000
● Kuchulukitsa: 1.322 g / cm3
● Logp: -0.93680
● Kufatsa tepi: z kwings ku + 30C
● Solsubility.:aous acid (pang'ono), DMSO (pang'ono, otenthedwa, yunisited), methanol (pang'ono,
● Madzi osungunuka.:Asable m'madzi otentha
● xlogp3: -1.1
● Hydrogen Conser Wopereka: 2
● Okondedwa
● Mgwirizano wosinthika: 0
● Misa yeniyeni: 112.02727375
● Atomu Olemera: 8
● Zovuta: 161
Zambiri zopanda chitetezo
● Petergogm (s):
Xi
● Ma Code Zowopsa: XI
● Nkhani zotetezeka: 22-24 / 25
Chofunika
Maphunziro a Mankhwala:Othandizira zachilengedwe -> acid a ma acid a ma acid ndi zotumphukira
Kumwetulira kwa Canonan:C1 = cnc (= o) nc1 = o
Mankhwala aposachedwa:Phunzirani zonona 0.1% zonona zonona (UTC) popewa kuwononga mapazi
Mayesero a EU posachedwa;Onderzoek Naar de mafamu van Uracil na orale oraleenation bij.
Mayesero a Ciph aposachedwa a Niph: Gawo la II II chiyeso cha mafuta oracil popewa matenda a carcitabine omwe amapezeka pansi pa phazi (HFS) :.
Gwiritsani Ntchito:Chifukwa cha kafukufuku wofufuza, kaphatikizidwe mankhwala osokoneza bongo; Kugwiritsidwa ntchito ngati gawo lapakatikati, omwe amagwiritsidwanso ntchito ngati kachilombo ka orterogenis nayitrogenius mpaka ku RNA Nyengo. Antineoplastical kafukufuku wambiri. Uracil (Lamiyuudine EP Kupukuza F) ndi maziko a nitrogenious pa RNA Ndege.
Kufotokozera:Uracil ndi PYNIDIDIINE Bair ndi gawo lofunikira la RNA komwe limamangiriza ndi madenine kudzera pamalande a hydrogen. Amasinthidwa kukhala artidine a Nockide kudzera kuphatikizira nthiti ya riboni, kenako mpaka ku nucleotide Uridine monophphathete pofika gulu la phosphate.
Mawu owonjezera
Uracil ndi wolemera yemwe ali m'banja la Pyrixidine. Ndi herucyclic molekyutic molekyutic yopangidwa ndi mphete ya pisitanti yokhala ndi ma atomu awiri oyandikana nawo. Uracil ili ndi njira ya mankhwala C4H4N2O2 ndi zolemera za 112.09 g / Mol.
UCHARIL ndi amodzi mwa ma nuclease anayi omwe amapezeka mu genetic ya RNA (ribonocleic asidi). Imagwira ntchito yofunika kwambiri mu kapangidwe ka protein ndi majini. Ku RNA, Uracil awiriawiri ndi Adenine kudzera kuphatikizika hydrogen, ndikupanga ma bondol awiri a hydrogen, ndipo malo osungirako awa amathandizira kuyika zidziwitso za majini.
Uracil ukhoza kupezekanso m'mamolekyu ena ofunikira azachilengedwe. Mwachitsanzo, ndizofunikira kwambiri kwa molekyulu yonyamula mphamvu yotchedwa ATP (Adenosine TripoSphate). Kuchulukitsa kwa Uracl, monga 5-fluorouracil, zakhala zikugwiritsidwa ntchito ngati othandizira anticancer chifukwa cha kusokoneza kwawo kwa DNA ndikugawa kwa cell.
Kuphatikiza pa tanthauzo lake lachilengedwe, Uracil limagwiritsa ntchito mankhwala osiyanasiyana a mankhwala ndi mafakitale. Amagwiritsidwa ntchito ngati chinthu choyambira pa kaphatikizidwe wa mankhwala a mankhwala, abulamu, ndi utoto. Kuchokera ku Uracil kumagwiritsidwanso ntchito popanga herbicides ndi fungicides. Kuphatikiza apo, kusinthika kumatha kugwiritsidwa ntchito ngati cholembera mumachenjezidwe komanso ngati chida chofufuzira zinthu molecular.
Uracil ndi cholimba choyera chomwe chimasungunuka m'madzi. Imakhala yokhazikika m'makhalidwe abwinobwino koma imatha kusintha mankhwala, monga oxidation ndi m'malo mwake zimachitika, mogwirizana. Pawiri ili ndi malo osungunuka 335-338°C ndi malo otentha a 351-357°C.
Ponseponse, Uracil ndi chinthu chofunikira kwambiri muchilengedwe cha RNA ndipo ali ndi ntchito zofunikira mu mafakitale achilengedwe komanso mankhwala.
Karata yanchito
Uracil ali ndi ntchito zingapo m'minda yosiyanasiyana, kuphatikiza:
Makampani opanga mankhwala:Uracil ndi zotumphuka zake zakhala zikugwiritsidwa ntchito popanga mankhwala osokoneza bongo. Mwachitsanzo, 5-fluorouracil ndi mankhwala omwe nthawi zambiri amagwiritsidwa ntchito pochiza mitundu ina ya khansa. Mankhwala osokoneza bongo ophatikizika, monga Idoxuridine ndi Trifluridine, amagwiritsidwa ntchito pochiza matenda a virus.
Ulimi:Zosasinthika za Uracl zimagwiritsidwa ntchito popanga herbicides ndi fungicides. Izi zimathandizira kuwongolera kukula kwa namsongole ndikuteteza mbewu ku matenda oyamba ndi fungus.
Chemistry Chemistry:Uracil nthawi zambiri amagwiritsidwa ntchito ngati chikhomo cha chromatographic kapena muyezo wamkati mwazowunika. Itha kugwiritsidwa ntchito ngati gawo lowerengera kuti mudziwe nthawi yosungirayo komanso yopanga zina mwazomwe zimachitika.
Kafukufuku wa Soulogy:UCHACIL imagwiritsidwa ntchito m'machitidwe osiyanasiyana azomwe amasintha, monga momwe mungachitire polymem (PCR), DNE), DNA, ndi Mutageneis yoyendetsedwa. Imakhala ngati template ya DNA synthesis kapena ngati gawo lopanga masinthidwe apadera a DNA.
Makampani Ogulitsa Chakudya:UCHARIL nthawi zina imagwiritsidwa ntchito ngati kuwonjezera kwa mafuta opanga zakudya, makamaka popanga zakudya zokongoletsera ndi zakumwa.
Zodzikongoletsera:Kuchokera ku Uracil kumagwiritsidwa ntchito pazodzikongoletsera zodzikongoletsera za kunyowa ndi khungu. Amatha kuthandiza kukonza khungu ndi kuteteza ku zovuta zachilengedwe.
Kafukufuku ndi Chitukuko:UCHACIL imagwiritsidwanso ntchito pofufuza za mankhwala biochemical monga chofufumitsa kapena chapakati pazinthu zina ndi zochitika zachilengedwe kapena pophunzira zanyukisi a acitabolism.
Mapulogalamu osiyanasiyana a Uracil amawonetsa kufunikira kwake komwe kumafunikira minda, ulimi, umagwirira, ndi biotechnology. Ofufuzawo akupitilizabe kufufuza njira zatsopano zokakamira zomwe zimapangitsa kuti zizipita patsogolo kwambiri m'malo awa.
